Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821061 | 0.91 | TDP1 (0.53) | TDP1MEN1GAAMAPTRAD52 | |
| SCHEMBL6817497 | 0.87 | TDP1 (0.52) | TDP1MEN1GAAMAPTRAD52 | |
| SCHEMBL6817304 | 0.86 | ESR1 (0.43) | TDP1S1PR3MAPK8MAPK9KDM4E | |
| SCHEMBL6820282 | 0.81 | TDP1 (0.42) | TDP1MEN1GAAMAPTRAD52 | |
| SCHEMBL6821006 | 0.81 | TDP1 (0.52) | TDP1MEN1GAAMAPTRAD52 | |
| SCHEMBL6820985 | 0.80 | KMT2A (0.56) | TDP1MEN1GAAMAPTRAD52 | |
| SCHEMBL6820713 | 0.79 | TDP1 (0.41) | TDP1MEN1GAAMAPTRAD52 | |
| SCHEMBL3928794 | 0.78 | HTR6 (0.50) | KDM4EHTR1ADRD3HTR6 | |
| SCHEMBL6820242 | 0.78 | KDM4E (0.45) | TDP1GAAALDH1A1KDM4E | |
| SCHEMBL6917019 | 0.77 | ESR1 (0.48) | TDP1MEN1GAAMAPTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |