Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 13/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922144 | 0.87 | ESR1 (0.51) | KMT2ATSHRMAPK1PLA2G2APLA2G1B | |
| SCHEMBL6821061 | 0.86 | TDP1 (0.53) | KMT2ATSHRMAPK1PLA2G2ATDP1 | |
| SCHEMBL6821006 | 0.85 | TDP1 (0.52) | KMT2ATSHRMAPK1PLA2G2ATDP1 | |
| SCHEMBL6820735 | 0.85 | PLA2G2A (0.46) | KMT2ATSHRMAPK1PLA2G2APLA2G1B | |
| SCHEMBL6817497 | 0.85 | TDP1 (0.52) | KMT2AMAPK1PLA2G2AHTR6TDP1 | |
| SCHEMBL6817320 | 0.80 | TDP1 (0.47) | KMT2APLA2G2AHTR6TDP1MEN1 | |
| SCHEMBL6821103 | 0.79 | ESR1 (0.50) | KMT2APLA2G2AHTR6TDP1MAPT | |
| SCHEMBL3560763 | 0.78 | HTR6 (0.72) | HTR6 | |
| SCHEMBL6817298 | 0.78 | LMNA (0.61) | KMT2ATSHRPLA2G2AHTR6MEN1 | |
| SCHEMBL6821057 | 0.76 | HTR6 (0.69) | PLA2G2AHTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |