Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841620 | 0.79 | HTR6 (0.46) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| SCHEMBL146530 | 0.74 | GPR84 (0.57) | KDM4ENQO2KMT2AGPR3ALKBH5 | |
| SCHEMBL29473770 | 0.74 | GPR84 (0.57) | KDM4ENQO2KMT2AGPR3ALKBH5 | |
| SCHEMBL2957635 | 0.74 | SLC6A2 (0.41) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| SCHEMBL8927744 | 0.73 | MEN1 (0.46) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| SCHEMBL6114157 | 0.73 | SLC6A2 (0.43) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| SCHEMBL2790587 | 0.73 | SLC6A2 (0.43) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| SCHEMBL27324374 | 0.73 | SLC6A2 (0.43) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| SCHEMBL14141407 | 0.73 | SLC6A2 (0.43) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| SCHEMBL151528 | 0.73 | IDO1 (0.40) | KDM4EMEN1KMT2AGPR3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103339111-B | Bicyclic acetyl-CoA carboxylase inhibitors | NOVARTIS AG (CH) | 2015-12-16 | — | — | CN | claimed |
| CN-104854087-A | As P2X7Indole carboxamide derivatives of receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2015-08-19 | — | — | CN | claimed |
| US-10876068-B2 | 2,3,6-trimethylcyclohexanol as a scenting and/or flavoring agent | SYMRISE AG (DE) | 2020-12-29 | — | — | US | disclosed |
| CN-104725295-B | Aromatic heterocyclic derivatives and its application on drug | 广东东阳光药业有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-105555763-A | Indole-carboxamide derivatives | HOFFMANN LA ROCHE | 2016-05-04 | — | — | CN | disclosed |
| CN-105246895-A | Piperazino [1, 2-a ] indol-1-ones and [1, 4] diaza-o [1, 2-a ] indol-1-ones | HOFFMANN LA ROCHE | 2016-01-13 | — | — | CN | disclosed |
| CN-104854087-A | As P2X7Indole carboxamide derivatives of receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2015-08-19 | — | — | CN | disclosed |
| CN-104725295-A | Aromatic heterocycle derivatives and application thereof to drugs | GUANGDONG HEC PHARMACEUTICAL | 2015-06-24 | — | — | CN | disclosed |
| CN-104540829-A | Piperazino[1,2-a]indol-1-ones and [1,4]diazepino[1,2-a]indol-1-one | HOFFMANN LA ROCHE | 2015-04-22 | — | — | CN | disclosed |
| EP-0888543-A4 | AZATIDE PEPTIDOMIMETICS | SCRIPPS RESEARCH INST (US) | 2004-04-07 | — | — | EP | disclosed |
| US-6664372-B1 | Solution phase synthesis on a soluble homopolymer support by reacting tert-butoxycarbonyl-protected aza-amino acids with bis(pentafluorophenyl) carbonate as carbonyl activation element and coupling to support; combinatorial chemistry | THE SCRIPPS RESEARCH INSTITUTE | 2003-12-16 | — | — | US | disclosed |
| EP-0888543-A1 | AZATIDE PEPTIDOMIMETICS | The Scripps Research Institute (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997035199-A9 | AZATIDE PEPTIDOMIMETICS | — | 1997-12-11 | — | — | WO | disclosed |
| WO-1997035199-A1 | AZATIDE PEPTIDOMIMETICS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10876068-B2 | 2,3,6-trimethylcyclohexanol as a scenting and/or flavoring agent | TAS2R3, TAS2R5, TAS2R13 | SLC6A2 2986/4885KDM4E 865/4885NQO2 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.