SCHEMBL2957635

SCHEMBL2957635

Cc1cn(P(Cl)n2cc(C)c3ccccc32)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 2/20 0.40
NQO2 P16083 1/20 0.40
HTR6 P50406 1/20 0.39
GPR3 P46089 1/20 0.38
SLC6A4 P31645 3/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.37
FTO Q9C0B1 1/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2A6 P11509 2/20 0.37
ALDH1A1 P00352 1/20 0.37
FABP4 P15090 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11707913 0.81 SLC6A2 (0.42) SLC6A2MEN1KMT2AKDM4ENQO2
SCHEMBL13698826 0.81 SLC6A2 (0.42) SLC6A2MEN1KMT2AKDM4ENQO2
SCHEMBL3841620 0.76 HTR6 (0.46) SLC6A2MEN1KMT2AKDM4ENQO2
SCHEMBL6817359 0.74 SLC6A2 (0.43) SLC6A2MEN1KMT2AKDM4ENQO2
SCHEMBL29473770 0.71 GPR84 (0.57) KMT2AKDM4ENQO2GPR3ALKBH5
SCHEMBL146530 0.71 GPR84 (0.57) KMT2AKDM4ENQO2GPR3ALKBH5
SCHEMBL11954801 0.71 SLC6A2 (0.41) SLC6A2MEN1KMT2AKDM4ENQO2
SCHEMBL12159487 0.70 SLC6A2 (0.35) SLC6A2MEN1KMT2AKDM4ENQO2
SCHEMBL14141407 0.70 SLC6A2 (0.43) SLC6A2MEN1KMT2AKDM4ENQO2
SCHEMBL2790587 0.70 SLC6A2 (0.43) SLC6A2MEN1KMT2AKDM4ENQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9795952-B2 Bidentate ligands for hydroformylation of ethylene DOW TECHNOLOGY INVESTMENTS LLC (US) 2017-10-24 US disclosed
US-9795952-B2 Bidentate ligands for hydroformylation of ethylene DOW TECHNOLOGY INVESTMENTS LLC (US) 2017-10-24 US disclosed
US-20150328628-A1 Bidentate Ligands for Hydroformylation of Ethylene THE DOW CHEMICAL COMPANY 2015-11-19 US disclosed
US-20150328628-A1 Bidentate Ligands for Hydroformylation of Ethylene THE DOW CHEMICAL COMPANY 2015-11-19 US disclosed
WO-2014088800-A1 BIDENTATE LIGANDS FOR HYDROFORMYLATION OF ETHYLENE DOW TECHNOLOGY INVESTMENTS LLC (US) 2014-06-12 WO disclosed
EP-2740535-A1 Bidentate ligands for hydroformylation of ethylene Dow Technology Investments LLC (US) 2014-06-11 EP disclosed
US-7767852-B2 Removal by salt formation BASF AKTIENGESELLSCHAFT (DE) 2010-08-03 US disclosed
US-7767852-B2 Removal by salt formation BASF AKTIENGESELLSCHAFT (DE) 2010-08-03 US disclosed
US-7767852-B2 Removal by salt formation BASF AKTIENGESELLSCHAFT (DE) 2010-08-03 US disclosed
US-20080083606-A1 preparing aminodihalophosphines, diaminohalophosphines, triaminophosphines, phosphorous ester diamides, aminophosphines, diaminophosphines, phosphorous ester amide halides and aminophosphine halides with elimination of an acid in the presence of an auxiliary base BASF AKTIENGESELLSCHAFT (DE) 2008-04-10 US disclosed
US-20080083606-A1 preparing aminodihalophosphines, diaminohalophosphines, triaminophosphines, phosphorous ester diamides, aminophosphines, diaminophosphines, phosphorous ester amide halides and aminophosphine halides with elimination of an acid in the presence of an auxiliary base BASF AKTIENGESELLSCHAFT (DE) 2008-04-10 US disclosed
US-20080083606-A1 preparing aminodihalophosphines, diaminohalophosphines, triaminophosphines, phosphorous ester diamides, aminophosphines, diaminophosphines, phosphorous ester amide halides and aminophosphine halides with elimination of an acid in the presence of an auxiliary base BASF AKTIENGESELLSCHAFT (DE) 2008-04-10 US disclosed
EP-1470136-B1 METHOD FOR THE SEPARATION OF ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF IONIC FLUIDS BASF AG (DE) 2007-03-28 EP disclosed
US-20050020857-A1 Removal by salt formation BASF AKTIENGESELLSCHAFT (DE) 2005-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020857-A1 Removal by salt formation PHOSPHO1, AASDHPPT, INPP5B SLC6A2 1800/4885MEN1 1135/4885KMT2A 1005/4885
US-20150328628-A1 Bidentate Ligands for Hydroformylation of Ethylene HRH4, HRH3, H1-4 SLC6A2 3329/4885MEN1 3609/4885KMT2A 2873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.