Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732827 | 0.86 | KMT2A (0.48) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL1020760 | 0.80 | MAPT (0.67) | MAPTPOLBL3MBTL1TLR8HSD11B1 | |
| SCHEMBL3667279 | 0.76 | DPP4 (0.61) | MAPTPOLBCARM1PRMT6ALDH1A1 | |
| SCHEMBL31447962 | 0.75 | HSPB1 (0.53) | MAPTALDH1A1TLR8TDP1 | |
| SCHEMBL6918825 | 0.75 | HSPB1 (0.53) | MAPTALDH1A1TLR8TDP1 | |
| SCHEMBL433497 | 0.75 | HTT (0.58) | MAPTPOLBALDH1A1PGRHSD17B10 | |
| SCHEMBL9720036 | 0.75 | HTT (0.58) | MAPTPOLBALDH1A1PGRHSD17B10 | |
| SCHEMBL6826223 | 0.75 | MAOA (0.50) | MAPTPOLBCARM1PRMT6ALDH1A1 | |
| SCHEMBL11402635 | 0.75 | MEN1 (0.48) | CARM1PRMT6ALDH1A1TLR8RHEB | |
| SCHEMBL31448129 | 0.75 | MAOA (0.50) | MAPTPOLBCARM1PRMT6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |