Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433497 | 1.00 | HTT (0.58) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL31244 | 0.91 | SOS1 (0.64) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL9536733 | 0.91 | SOS1 (0.64) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL1133769 | 0.91 | PGR (0.53) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL3109128 | 0.89 | HTT (0.61) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL1133770 | 0.89 | MMP2 (0.50) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL3913682 | 0.89 | HTT (0.48) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL1656016 | 0.89 | MMP1 (0.50) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL924893 | 0.89 | PKM (0.59) | HTTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL1133721 | 0.89 | HTT (0.50) | HTTALDH1A1HSD17B10TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110894-A | Thermoplastic films and fibers of high strength and thermal stability | THE DOW CHEMICAL COMPANY (US) | 1992-05-05 | — | — | US | disclosed |