Sugi Predict

Sugi Predict / Compounds / SCHEMBL433497

SCHEMBL433497

SCHEMBL433497

O=S(=O)(Cl)c1ccc(Oc2ccc(S(=O)(=O)Cl)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 8/20 0.58
▸ ALDH1A1 P00352 6/20 0.58
▸ HSD17B10 Q99714 2/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ SMN1; SMN2 Q16637 8/20 0.52
▸ LMNA P02545 8/20 0.52
▸ NPC1 O15118 2/20 0.52
▸ RAB9A P51151 2/20 0.52
▸ TP53 P04637 1/20 0.52
▸ MAPT P10636 1/20 0.52
▸ TSHR P16473 1/20 0.52
▸ XBP1 P17861 1/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ MDM2 Q00987 1/20 0.52
▸ SOS1 Q07889 4/20 0.50
▸ POLB P06746 1/20 0.45
▸ MEN1 O00255 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ PGR P06401 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720036 1.00 HTT (0.58) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL31244 0.91 SOS1 (0.64) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL9536733 0.91 SOS1 (0.64) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL1133769 0.91 PGR (0.53) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL1133721 0.89 HTT (0.50) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL3913682 0.89 HTT (0.48) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL1133770 0.89 MMP2 (0.50) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL282256 0.89 SOS1 (0.66) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL1656016 0.89 MMP1 (0.50) HTTALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL924893 0.89 PKM (0.59) HTTALDH1A1SMN1; SMN2LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302760-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2025-10-02 — — US claimed
CN-118105923-A Production process and equipment of 4,4' -oxo-bis-benzenesulfonyl hydrazide 嘉兴市金利化工有限责任公司 2024-05-31 — — CN claimed
EP-4323462-A1 CMP COMPOSITIONS FOR POLISHING DIELECTRIC MATERIALS Entegris, Inc. (US) 2024-02-21 — — EP claimed
CN-116903850-A Ionic polymer electrolyte LiPSBI, preparation method and application thereof 山东正熵能源科技有限公司 2023-10-20 — — CN claimed
CN-116742276-A Composite solid polymer electrolyte CSPEs diaphragm and preparation method and application thereof 山东正熵能源科技有限公司 2023-09-12 — — CN claimed
CN-116742115-A Preparation and application of ionic polymer electrolyte ion-PE and ionic polymer nanofiber membrane 山东正熵能源科技有限公司 2023-09-12 — — CN claimed
CN-114105834-B Preparation method of N, N, N, N-tetraallyloxy bis-benzenesulfonamide 寿光诺盟化工有限公司 2023-04-25 — — CN claimed
CN-115612160-B Preparation method of heat-conducting nylon composite material 广东永鑫华新型材料有限公司 2023-03-10 — — CN claimed
CN-115612160-A Preparation method of heat-conducting nylon composite material 广东永鑫华新型材料有限公司 2023-01-17 — — CN claimed
CN-217856122-U A reation kettle for producing 4,4' -oxo-diphenyl sulfonyl chloride 嘉兴市汇通科技有限公司 2022-11-22 — — CN claimed
US-20220332977-A1 CMP COMPOSITIONS FOR POLISHING DIELECTRIC MATERIALS ENTEGRIS, INC. 2022-10-20 — — US claimed
CN-114436907-A Environment-friendly preparation method of foaming agent 内蒙古锦洋化学工业有限公司 2022-05-06 — — CN claimed
CN-114105834-A Preparation method of N, N, N, N-tetraallyloxybisbenzenesulfonamide 寿光诺盟化工有限公司 2022-03-01 — — CN claimed
US-20060258867-A1 Transition metal complexes, especially iron complexes, used as a catalyst component in the polymerisation of olefins IC INNOVATIONS LTD. (GB) 2006-11-16 — — US claimed
US-7098296-B2 Preparation of polymeric aryl sulfonamide SUN CHEMICAL CORPORATION (US) 2006-08-29 — — US claimed
WO-2004081020-A1 TRANSITION METAL COMPLEXES, ESPECIALLY IRON COMPLEXES, USED AS A CATALYST COMPONENT IN THE POLYMERISATION OF OLEFINS IC INNOVATIONS LTD (GB) 2004-09-23 — — WO claimed
US-20040006156-A1 Preparation of polymeric aryl sulfonamide SUN CHEMICAL CORPORATION 2004-01-08 — — US claimed
WO-2001068726-A1 ATOM TRANSFER RADICAL POLYMERISATION CATALYST BP CHEMICALS LIMITED (GB) 2001-09-20 — — WO claimed
US-4765898-A HEAT RESISTANCE; SEPARATION BRINE AND ALSO WATER/ORGANIC SOLVENT SOLUTIONS STORK FRIESLAND B.V. (NL) 1988-08-23 — — US claimed
EP-0209935-A1 Semipermeable membranes based on polymers containing sulphonate groups STORK FRIESLAND B.V. (NL) 1987-01-28 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258867-A1 Transition metal complexes, especially iron complexes, used as a catalyst component in the polymerisation of olefins NR1I3, OPRD1, NR1I2 HTT 4511/4885ALDH1A1 3998/4885HSD17B10 1775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.