Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 2/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564471 | 0.82 | PTPN1 (0.61) | PTPN1DUSP3TP53KDM4EMEN1 | |
| SCHEMBL5729094 | 0.79 | ESR1 (0.45) | RAB9AMAPTNPC1HPGDSMN1; SMN2 | |
| SCHEMBL405325 | 0.76 | S1PR1 (0.46) | PTPN1KDM4E | |
| SCHEMBL4395634 | 0.75 | ALDH1A1 (0.54) | PTPN1RAB9AMAPTNPC1HPGD | |
| SCHEMBL6834238 | 0.74 | KAT2B (0.45) | PTPN1 | |
| SCHEMBL5730462 | 0.73 | ESR2 (0.43) | RAB9AMAPTNPC1HPGDSMN1; SMN2 | |
| SCHEMBL19668565 | 0.73 | KDM4E (0.42) | PTPN1RAB9AMAPTNPC1HPGD | |
| SCHEMBL1686474 | 0.72 | PTPN1 (0.45) | PTPN1RAB9ADUSP3MAPTNPC1 | |
| SCHEMBL1686554 | 0.72 | PTPN1 (0.45) | PTPN1DUSP3MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1686409 | 0.72 | ALOX5AP (0.50) | PTPN1DUSP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | PTPN1 3166/4885RAB9A 4337/4885DUSP3 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.