Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814011 | 0.86 | ACLY (0.38) | GRIK1ACLYDNMT3ASORT1AKR1C2 | |
| SCHEMBL6818060 | 0.85 | AKR1C2 (0.51) | SORT1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6818553 | 0.85 | AKR1C2 (0.50) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6818795 | 0.84 | CA12 (0.43) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6833190 | 0.83 | HIF1A (0.47) | GRIK1ACLYDNMT3ASORT1AKR1C2 | |
| SCHEMBL6818370 | 0.79 | METAP2 (0.44) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6814346 | 0.75 | ALB (0.42) | ACLYAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL1307332 | 0.74 | PPARG (0.71) | GRIK1ACLYDNMT3ASORT1AKR1C2 | |
| SCHEMBL6819170 | 0.74 | MEN1 (0.44) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL1307201 | 0.74 | KCNK2 (0.64) | GRIK1ACLYDNMT3AAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |