Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139621 | 0.83 | MAPT (0.53) | ABCB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6161980 | 0.83 | MAPT (0.53) | ABCB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL16018989 | 0.83 | ABCB1 (0.68) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL6813969 | 0.80 | NPC1 (0.55) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL22711476 | 0.79 | PDE2A (0.46) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL16019017 | 0.79 | MAPT (0.66) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL31715924 | 0.78 | MAOB (0.54) | NPC1RAB9AGAAALDH1A1SGMS2 | |
| Lithium SCHEMBL31715835 | 0.77 | MAOB (0.53) | NPC1RAB9AGAAALDH1A1SGMS2 | |
| SCHEMBL12301149 | 0.77 | ABCB1 (0.60) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL18297720 | 0.76 | MAOB (0.54) | GAAALDH1A1LMNAMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | ABCB1 1171/4885NPC1 3778/4885RAB9A 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.