Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139621 | 1.00 | MAPT (0.53) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL6818008 | 0.83 | ABCB1 (0.55) | HTR1AADRA1DADRA1AADRA1BSGMS2 | |
| SCHEMBL31715924 | 0.83 | MAOB (0.54) | MAPK1L3MBTL1SGMS2HPGDGAA | |
| Lithium SCHEMBL31715835 | 0.82 | MAOB (0.53) | MAPK1L3MBTL1SGMS2HPGDGAA | |
| SCHEMBL448079 | 0.81 | MAOB (0.57) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL2248786 | 0.81 | MAPT (0.53) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL22711497 | 0.79 | MAPT (0.43) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL339812 | 0.79 | MAPT (0.71) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL22219370 | 0.78 | MAPT (0.55) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL30378353 | 0.76 | MAPT (0.45) | MAPTMAPK1TDP1L3MBTL1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907297-A | Method for preparing benzodihydrofuran derivative by visible light catalysis of 2-alkynyl aryl ether and sulfonyl chloride in series | 湖南警察学院 | 2022-08-16 | — | — | CN | disclosed |
| US-10385063-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-20 | — | — | US | disclosed |
| EP-3239142-B1 | CONDENSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-9975903-B2 | Condensed heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-22 | — | — | US | disclosed |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20170349605-A1 | CONDENSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-07 | — | — | US | disclosed |
| EP-3239142-A1 | CONDENSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2017-11-01 | — | — | EP | disclosed |
| US-20050143578-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2005-06-30 | — | — | US | disclosed |
| EP-1434772-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2005-05-04 | — | — | EP | disclosed |
| US-20040192914-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-09-30 | — | — | US | disclosed |
| EP-1434772-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003031434-A1 | COMPOUNDS AND METHODS | SMITH KLINE BEECHAM CORPORATION (US) | 2003-04-17 | — | — | WO | disclosed |
| EP-0834499-B1 | Process for the preparation of aromatic vinyl compounds | DAINIPPON INK & CHEMICALS (JP) | 2001-07-25 | — | — | EP | disclosed |
| EP-0834499-A1 | Process for the preparation of aromatic vinyl compounds | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-04-08 | — | — | EP | disclosed |
| EP-0489877-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | UPJOHN CO (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5302613-A | Antiatheroscleroic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones | THE UPJOHN COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| US-5252735-A | Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones | THE UPJOHN COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0489877-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES. | UPJOHN CO (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1992000290-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | THE UPJOHN COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192914-A1 | Compounds and methods | METAP2, METAP1, DNPEP | MAPT 2605/4885MAPK1 3352/4885TDP1 3624/4885 |
| US-10385063-B2 | Herbicidal compounds | DDT, DAO, HPD | MAPT 3777/4885MAPK1 2181/4885TDP1 1729/4885 |
| US-20050143578-A1 | Compounds and methods | METAP2, METAP1, DNPEP | MAPT 2341/4885MAPK1 3572/4885TDP1 4007/4885 |
| US-20170349605-A1 | CONDENSED HETEROCYCLIC COMPOUND | VIP, TMPRSS15, MMP2 | MAPT 4104/4885MAPK1 1254/4885TDP1 4680/4885 |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | DDT, DAO, HPD | MAPT 3748/4885MAPK1 2140/4885TDP1 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.