Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP12 | P39900 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24884876 | 0.97 | NOD1 (0.49) | NOD1MMP2MMP9MMP8MMP12 | |
| Hydrochloric Acid SCHEMBL15799637 | 0.95 | NOD1 (0.47) | NOD1MMP2MMP9MMP8MMP12 | |
| SCHEMBL24885095 | 0.95 | NOD1 (0.46) | NOD1MMP2MMP9MMP8MMP12 | |
| Benzene SCHEMBL4058883 | 0.86 | MMP9 (0.42) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL7416802 | 0.82 | HDAC1 (0.43) | NOD1MMP2MMP9MMP8MMP12 | |
| SCHEMBL7416795 | 0.82 | HDAC1 (0.43) | NOD1MMP2MMP9MMP8MMP12 | |
| Hydrochloric Acid SCHEMBL32662559 | 0.80 | HDAC1 (0.41) | NOD1MMP2MMP9MMP8MMP12 | |
| SCHEMBL31522342 | 0.80 | ITGB3 (0.51) | NOD1GPR84FFAR1MAPTLCK | |
| SCHEMBL6818957 | 0.80 | ITGB3 (0.51) | NOD1GPR84FFAR1MAPTLCK | |
| SCHEMBL8012073 | 0.79 | MMP2 (0.55) | MMP2MMP9CA2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |