Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376109 | 0.81 | L3MBTL1 (0.33) | ALDH1A1PARP1PARP10L3MBTL1ECE1 | |
| SCHEMBL5507844 | 0.79 | TSHR (0.42) | SMN1; SMN2CA14KMT2ACA1CA2 | |
| SCHEMBL2646187 | 0.79 | PARP1 (0.40) | SMN1; SMN2CA14PARP1PARP10KMT2A | |
| SCHEMBL10404573 | 0.79 | PARP1 (0.40) | SMN1; SMN2CA14PARP1PARP10KMT2A | |
| SCHEMBL8499223 | 0.79 | SLC1A3 (0.38) | ALDH1A1PARP1PARP10KMT2AALOX15 | |
| SCHEMBL2648364 | 0.79 | TSHR (0.42) | SMN1; SMN2CA14KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL3048944 | 0.77 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1CA14KMT2ACA1 | |
| Hydrochloric Acid SCHEMBL22164454 | 0.77 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1CA14KMT2ACA1 | |
| Hydrochloric Acid SCHEMBL6231526 | 0.77 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1CA14KMT2ACA1 | |
| Hydrochloric Acid SCHEMBL2646938 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA14KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38551-E1 | ADMINISTERING N-BENZYL-2- ACETAMIDO PROPIONAMIDE DERIVATIVES IN THE R CONFIGURATION, SUCH AS LACOSAMIDE | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2004-07-06 | — | — | US | disclosed |
| EP-1038522-B1 | Anticonvulsant enantiomeric amino acid derivatives | RES CORP TECHNOLOGIES INC (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-0888289-B1 | ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES | RES CORP TECHNOLOGIES INC (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1038522-A2 | Anticonvulsant enantiomeric amino acid derivatives | Research Corporation Technologies, Inc (US) | 2000-09-27 | — | — | EP | disclosed |
| US-5773475-A | DIPEPTIDES FOR CENTRAL NERVOUS SYSTEM DISORDERS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |