Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818703 | 0.83 | CCNC (0.36) | CYP2D6CYP2C9CYP2C19CYP3A4KMT2A | |
| SCHEMBL6704157 | 0.81 | NR4A2 (0.35) | CYP2D6CYP2C9CYP2C19GAAKMT2A | |
| SCHEMBL6818691 | 0.80 | CCNC (0.40) | CYP2D6CYP2C9CYP2C19CYP3A4CDC7 | |
| SCHEMBL6702617 | 0.76 | MMP13 (0.41) | MAPK1ROCK2RPS6KA5MAP4K4PRKCG | |
| SCHEMBL6819957 | 0.75 | NPC1 (0.46) | MAPK1ROCK2RPS6KA5MAP4K4PRKCG | |
| SCHEMBL6819967 | 0.72 | MMP13 (0.39) | MAPK1ROCK2RPS6KA5MAP4K4PRKCG | |
| SCHEMBL6819953 | 0.72 | MMP13 (0.38) | MAPK1ROCK2RPS6KA5MAP4K4PRKCG | |
| SCHEMBL6700620 | 0.69 | MMP13 (0.44) | MAPK1ROCK2RPS6KA5MAP4K4PRKCG | |
| SCHEMBL6289016 | 0.66 | SCD (0.43) | ALDH1A1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL6698728 | 0.66 | PTGER4 (0.47) | ALDH1A1MMP13SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014916-A1 | PYRIMIDINE FUSED BICYCLIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |