Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | TMPRSS11D | O60235 | 4/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12044849 | 0.85 | SLC1A3 (0.54) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL18696985 | 0.83 | ITGB3 (0.57) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL600046 | 0.83 | ALDH1A1 (0.52) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30309011 | 0.82 | ITGB3 (0.65) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1329533 | 0.81 | SLC1A3 (0.56) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6818050 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6821963 | 0.81 | HDAC3 (0.41) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4058881 | 0.80 | SLC1A3 (0.55) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1509338 | 0.80 | MMP9 (0.59) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6670868 | 0.80 | MMP9 (0.59) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |