Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.50 |
| ▸ | TUBB | P07437 | 8/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819105 | 0.85 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2450750 | 0.81 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6819481 | 0.81 | TSHR (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10393725 | 0.78 | HSD17B2 (0.47) | MAPK1ALDH1A1CYP2D6NQO1 | |
| SCHEMBL7374484 | 0.75 | TUBB4A (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10698804 | 0.74 | HTT (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL786660 | 0.73 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6955384 | 0.72 | TSHR (0.59) | MAPTMAPK1TSHRALDH1A1HPGD | |
| SCHEMBL7789471 | 0.72 | SMN1; SMN2 (0.48) | MAPTTSHRHPGD | |
| SCHEMBL13018859 | 0.72 | MEN1 (0.46) | MAPTTSHRALDH1A1HPGDNQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214311-B1 | NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-1214311-A1 | NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2002-06-19 | — | — | EP | disclosed |
| US-6296785-B1 | OPHTHALMIC AND CONTACT LENSES; WINDOWS, SAFETY GLASS FOR CARS | PPG INDUSTRIES OHIO, INC. | 2001-10-02 | — | — | US | disclosed |
| WO-2001019813-A1 | NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-03-22 | — | — | WO | disclosed |