SCHEMBL6819010

SCHEMBL6819010

Cn1ccc(OC(F)F)n1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.36
SCN4A P35499 1/20 0.36
GRIN2B Q13224 2/20 0.36
KCNH2 Q12809 1/20 0.36
KEAP1 Q14145 1/20 0.34
RXRA P19793 1/20 0.34
GRIN1 Q05586 1/20 0.34
JMJD6 Q6NYC1 1/20 0.33
CYP19A1 P11511 1/20 0.32
PDE10A Q9Y233 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19122772 0.76 CYP19A1 (0.37) KMT2ASCN4AKEAP1JMJD6CYP19A1
SCHEMBL23006749 0.76
SCHEMBL17662620 0.75 GABRP (0.36) KMT2ASCN4AKEAP1JMJD6CYP19A1
SCHEMBL19122410 0.75 KMT2A (0.33) KMT2ASCN4AKEAP1JMJD6
SCHEMBL16825528 0.75 KCNH2 (0.41) KMT2AKCNH2JMJD6PDE10A
SCHEMBL19121617 0.75 KMT2A (0.33) KMT2ASCN4AKEAP1JMJD6
SCHEMBL17662619 0.75 GABRP (0.36) KMT2ASCN4AKEAP1JMJD6CYP19A1
SCHEMBL19122039 0.72 CYP19A1 (0.37) KMT2AKEAP1JMJD6CYP19A1
SCHEMBL19121576 0.72 CYP19A1 (0.34) KMT2AKEAP1JMJD6CYP19A1
SCHEMBL16825368 0.72 ALOX15 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874466-B N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors PFIZER INC. (US) 2026-05-26 CN disclosed
US-20250333414-A1 HETARYL SUBSTITUTED INDAZOLES AND BENZIMIDAZOLES AS STING ANTAGONISTS AND THE USE THEREOF AS MEDICAMENT BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2025-10-30 US disclosed
CN-116874466-A N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors 辉瑞公司 2023-10-13 CN disclosed
CN-112672791-B N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors 辉瑞公司 2023-10-03 CN disclosed
WO-2004035563-A1 3-HETEROCYCLYLPYRIDINE DERIVATIVES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333414-A1 HETARYL SUBSTITUTED INDAZOLES AND BENZIMIDAZOLES AS STING ANTAGONISTS AND THE USE THEREOF AS MEDICAMENT STING1, MAVS, TBK1 KMT2A 3850/4885SCN4A 3432/4885GRIN2B 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.