Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.48 |
| ▸ | CTSK | P43235 | 14/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445439 | 0.90 | CTSS (0.56) | CTSSCTSKCTSLCTSBSYK | |
| SCHEMBL6446246 | 0.90 | CTSS (0.60) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6446763 | 0.88 | ESR1 (0.41) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6442192 | 0.85 | ESR1 (0.40) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6444049 | 0.84 | CTSS (0.50) | CTSSCTSKCTSLCTSBNQO2 | |
| SCHEMBL6442609 | 0.84 | CTSS (0.37) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6448170 | 0.83 | CTSK (0.42) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6446503 | 0.81 | SMN1; SMN2 (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6446330 | 0.80 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL5526272 | 0.80 | CTSS (0.67) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |