Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.58 |
| ▸ | MMP9 | P14780 | 7/20 | 0.58 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 6/20 | 0.52 |
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | CTSL | P07711 | 5/20 | 0.52 |
| ▸ | MMP13 | P45452 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.48 |
| ▸ | EEF2K | O00418 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL6818809 | 0.84 | EEF2K (0.42) | MMP9CTSSCTSLCTSBEEF2K | |
| SCHEMBL6818217 | 0.82 | ITGB3 (0.41) | MMP2MMP9CTSLMMP13MMP1 | |
| SCHEMBL2454204 | 0.74 | MMP2 (1.00) | MMP2MMP9ADAMTS4CTSSCTSK | |
| SCHEMBL32691785 | 0.74 | MMP2 (1.00) | MMP2MMP9ADAMTS4CTSSCTSK | |
| SCHEMBL32691761 | 0.72 | MMP2 (1.00) | MMP2MMP9ADAMTS4MMP13MMP1 | |
| SCHEMBL6545297 | 0.72 | MMP2 (1.00) | MMP2MMP9ADAMTS4MMP13MMP1 | |
| SCHEMBL1920507 | 0.72 | MMP2 (1.00) | MMP2MMP9ADAMTS4MMP13MMP1 | |
| SCHEMBL7453817 | 0.70 | ITGB1 (0.49) | MMP2MMP9ADAMTS4CTSSCTSK | |
| SCHEMBL6818852 | 0.70 | ITGB3 (0.39) | MMP2MMP9CTSLMMP13MMP1 | |
| SCHEMBL6818849 | 0.70 | ITGB3 (0.39) | MMP2MMP9CTSLMMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |