Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818852 | 1.00 | ITGB3 (0.39) | ITGB3ITGA2BITGAVSLC1A3SLC1A2 | |
| SCHEMBL6818217 | 0.87 | ITGB3 (0.41) | ITGB3ITGA2BITGAVSLC1A3SLC1A2 | |
| SCHEMBL6818411 | 0.84 | CTSB (0.48) | ITGB3ITGAVKMT2ACTSLCTSB | |
| SCHEMBL6818416 | 0.84 | CTSB (0.48) | ITGB3ITGAVKMT2ACTSLCTSB | |
| SCHEMBL6813988 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BITGAVSLC1A3SLC1A2 | |
| SCHEMBL6821963 | 0.79 | HDAC3 (0.41) | ITGB3ITGA2BITGAVSLC1A3SLC1A2 | |
| SCHEMBL6819162 | 0.77 | ALDH1A1 (0.43) | MMP9KMT2AMMP2MMP1 | |
| Benzene SCHEMBL6818809 | 0.73 | EEF2K (0.42) | EEF2KMMP9MMP8MMP14KMT2A | |
| SCHEMBL6092218 | 0.70 | LTA4H (0.54) | ITGB3ITGA2B | |
| SCHEMBL6819764 | 0.70 | MMP2 (0.58) | EEF2KMMP9MMP8MMP14CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |