Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147878 | 0.84 | POLB (0.50) | LMNASTAT3CYP2C19POLBACHE | |
| SCHEMBL6820157 | 0.82 | KMT2A (0.42) | LMNAEPHX1CYP2C19POLBMEN1 | |
| SCHEMBL6462542 | 0.82 | EPHX1 (0.40) | EPHX1ALDH1A1HTT | |
| SCHEMBL6711147 | 0.81 | EPHX1 (0.59) | ALOX5LMNAEPHX1CYP2C19SMN1; SMN2 | |
| SCHEMBL16750534 | 0.79 | ALOX5 (0.46) | ALOX5LMNAEPHX1STAT3CYP2C19 | |
| SCHEMBL26898446 | 0.79 | ALDH1A1 (0.50) | ALOX5LMNAEPHX1CYP2C19POLB | |
| SCHEMBL20826432 | 0.79 | L3MBTL1 (0.54) | LMNASTAT3POLBACHEALDH1A1 | |
| SCHEMBL6820306 | 0.79 | SMN1; SMN2 (0.44) | LMNACYP2C19POLBALDH1A1L3MBTL1 | |
| SCHEMBL2319893 | 0.79 | STAT3 (0.39) | ALOX5LMNASTAT3CYP2C19POLB | |
| SCHEMBL30699923 | 0.78 | CYP2C19 (0.51) | ALOX5LMNAEPHX1STAT3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026848-A1 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS | LUPIN LIMITED (IN) | 2004-04-01 | — | — | WO | disclosed |