Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | MB | P02144 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820001 | 0.79 | ALOX5 (0.42) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6820157 | 0.76 | KMT2A (0.42) | KMT2AMEN1BRD4CYP3A4TSHR | |
| SCHEMBL6462542 | 0.76 | EPHX1 (0.40) | HTTALDH1A1AOC3 | |
| SCHEMBL6711147 | 0.75 | EPHX1 (0.59) | SMN1; SMN2CYP2C19PKMHSD17B10LMNA | |
| SCHEMBL28867303 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EHTTL3MBTL1ALDH1A1 | |
| SCHEMBL7288784 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EHTTL3MBTL1ALDH1A1 | |
| SCHEMBL31357785 | 0.71 | CRHBP (0.55) | SMN1; SMN2HTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6930406 | 0.71 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL27254651 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EHTTL3MBTL1ALDH1A1 | |
| SCHEMBL28053185 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EHTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026848-A1 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS | LUPIN LIMITED (IN) | 2004-04-01 | — | — | WO | disclosed |