Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 10/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820079 | 0.82 | SRD5A1 (1.00) | SRD5A1 | |
| SCHEMBL6819849 | 0.81 | SRD5A1 (1.00) | SRD5A1MAPT | |
| SCHEMBL6819941 | 0.75 | SRD5A1 (0.46) | SRD5A1MAPTOPRM1OPRK1OPRL1 | |
| SCHEMBL6815448 | 0.75 | SRD5A1 (0.45) | SRD5A1MAPTOPRM1OPRK1OPRL1 | |
| SCHEMBL6820061 | 0.72 | SRD5A1 (0.71) | SRD5A1OPRM1OPRK1OPRL1 | |
| SCHEMBL6820470 | 0.71 | SRD5A1 (0.67) | SRD5A1NOTUM | |
| SCHEMBL6820047 | 0.70 | SRD5A1 (1.00) | SRD5A1MAPTROCK1LMNA | |
| SCHEMBL24893223 | 0.68 | ROCK1 (0.39) | SRD5A1MAPTOPRM1OPRK1OPRL1 | |
| SCHEMBL31469975 | 0.66 | OPRM1 (0.50) | OPRM1OPRK1OPRL1NOTUMNOS3 | |
| SCHEMBL6746146 | 0.66 | OPRM1 (0.50) | OPRM1OPRK1OPRL1NOTUMNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | claimed |
| US-6723850-B1 | N-ALKYLATION OF THE THIOAMIDE WITH A VINYL KETONE IN PRESENCE OF A STRONG BASE; 6-CHLORO-(1H)-3,4-DIHYDROQUINOLIN-2-THIONE REACTED WITH ETHYL VINYL KETONE | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-04-20 | — | — | US | disclosed |
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | disclosed |