Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820138 | 0.80 | SRD5A1 (0.64) | SRD5A1NOTUMMAPT | |
| SCHEMBL6820043 | 0.76 | SRD5A1 (0.67) | SRD5A1OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL6815740 | 0.76 | AADAT (0.38) | SRD5A1OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL6820083 | 0.75 | SRD5A1 (0.69) | SRD5A1OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL6822926 | 0.72 | OPRM1 (0.43) | SRD5A1OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL6823140 | 0.70 | NOTUM (0.45) | SRD5A1NOTUMLMNAMAPT | |
| SCHEMBL31469975 | 0.67 | OPRM1 (0.50) | OPRM1OPRK1OPRL1NOTUMNOS3 | |
| SCHEMBL6746146 | 0.67 | OPRM1 (0.50) | OPRM1OPRK1OPRL1NOTUMNOS3 | |
| SCHEMBL6823141 | 0.63 | SRD5A1 (1.00) | SRD5A1NOTUM | |
| SCHEMBL20335486 | 0.61 | ALDH1A1 (0.48) | OPRM1OPRK1OPRL1NOTUMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | claimed |
| US-6723850-B1 | N-ALKYLATION OF THE THIOAMIDE WITH A VINYL KETONE IN PRESENCE OF A STRONG BASE; 6-CHLORO-(1H)-3,4-DIHYDROQUINOLIN-2-THIONE REACTED WITH ETHYL VINYL KETONE | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-04-20 | — | — | US | disclosed |
| EP-1102765-B1 | PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2003-09-17 | — | — | EP | disclosed |