Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817336 | 0.89 | ALDH1A1 (0.41) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6821104 | 0.87 | ALDH1A1 (0.39) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6821026 | 0.86 | KDM4E (0.41) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6823561 | 0.86 | MEN1 (0.42) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3562851 | 0.84 | KDM4E (0.43) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6821066 | 0.83 | HTR7 (0.42) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6820214 | 0.81 | MEN1 (0.41) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6820281 | 0.80 | KDM4E (0.38) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6821012 | 0.80 | KDM4E (0.41) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6823922 | 0.79 | CNR1 (0.47) | MEN1KMT2ALMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |