Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820277 | 0.94 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL6817321 | 0.91 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL6821104 | 0.91 | ALDH1A1 (0.39) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL14953594 | 0.89 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL6824409 | 0.87 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL6921230 | 0.82 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL6821026 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL6820710 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL6820673 | 0.81 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL6820274 | 0.80 | HTR7 (0.39) | KDM4EALDH1A1HTR7LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |