Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
| ▸ | CNR2 | P34972 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823561 | 0.89 | MEN1 (0.42) | CNR2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6820214 | 0.88 | MEN1 (0.41) | CNR1CNR2MEN1KMT2AHPGD | |
| SCHEMBL6817324 | 0.88 | HTR6 (0.43) | CNR1CNR2MEN1KMT2ATSHR | |
| SCHEMBL6821066 | 0.87 | HTR7 (0.42) | CNR1CNR2MEN1KMT2ALMNA | |
| SCHEMBL6817298 | 0.86 | LMNA (0.61) | MEN1KMT2ATSHRLMNACYP1A2 | |
| SCHEMBL3557435 | 0.82 | HPGD (0.47) | MEN1KMT2ATSHRLMNACYP1A2 | |
| SCHEMBL6821035 | 0.80 | HTR6 (0.52) | MEN1KMT2APLA2G2AHTR6 | |
| SCHEMBL6820274 | 0.79 | HTR7 (0.39) | MEN1KMT2ALMNACYP1A2CYP2D6 | |
| SCHEMBL6821026 | 0.78 | KDM4E (0.41) | MEN1KMT2ALMNASMN1; SMN2TDP1 | |
| SCHEMBL3563162 | 0.78 | HTR6 (0.54) | MEN1KMT2ACYP2D6HTR6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |