Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562785 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL6817321 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL6821104 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL6817336 | 0.88 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL6820229 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL6820710 | 0.82 | KDM4E (0.41) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6820281 | 0.81 | KDM4E (0.38) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL14953594 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL6821012 | 0.79 | KDM4E (0.41) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL3559969 | 0.78 | HTR6 (0.37) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |