Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 9/20 | 0.56 |
| ▸ | EDNRB | P24530 | 6/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846856 | 0.81 | CASP1 (0.51) | EDNRAEDNRBCASP1ALOX5APFEN1 | |
| SCHEMBL6823510 | 0.80 | EDNRA (0.48) | EDNRAEDNRBCASP1ALOX5APFEN1 | |
| SCHEMBL29537027 | 0.79 | CA2 (0.58) | EDNRAEDNRBCASP1PTGS2ACLY | |
| SCHEMBL1767981 | 0.79 | CA2 (0.58) | EDNRAEDNRBCASP1PTGS2ACLY | |
| SCHEMBL937206 | 0.78 | PTGS2 (0.61) | EDNRAEDNRBCASP1PTGS2ACLY | |
| SCHEMBL29415408 | 0.78 | PTGS2 (0.61) | EDNRAEDNRBCASP1PTGS2ACLY | |
| SCHEMBL1968159 | 0.78 | ALOX5AP (0.59) | EDNRAEDNRBCASP1ALOX5APFEN1 | |
| SCHEMBL418847 | 0.77 | CASP1 (0.51) | EDNRAEDNRBCASP1ALOX5APFEN1 | |
| SCHEMBL10780146 | 0.77 | CASP1 (0.51) | EDNRAEDNRBCASP1ALOX5APFEN1 | |
| SCHEMBL15668311 | 0.77 | CASP1 (0.51) | EDNRAEDNRBCASP1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |