SCHEMBL3562785

SCHEMBL3562785

CC(=O)n1c(-c2ccccc2)c(OCCN(C)C)c2cc(Br)cc(Br)c21

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.42
KDM4E B2RXH2 8/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
TACR3 P29371 2/20 0.39
KCNH2 Q12809 1/20 0.39
HTR7 P34969 2/20 0.38
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CCNE2 O96020 1/20 0.35
CCNE1 P24864 1/20 0.35
CDK2 P24941 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6820673 0.91 ALDH1A1 (0.40) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL14953594 0.90 KDM4E (0.41) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL6821104 0.89 ALDH1A1 (0.39) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL3561464 0.85 ALDH1A1 (0.45) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL3562851 0.83 KDM4E (0.43) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL3559969 0.82 HTR6 (0.37) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL3562280 0.81 CHRM2 (0.36) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL3567877 0.81 HTR7 (0.37) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL6817321 0.81 KDM4E (0.39) ALDH1A1KDM4ELMNASMN1; SMN2KMT2A
SCHEMBL3556742 0.81 KDM4E (0.43) ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567492-B1 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES SUVEN LIFE SCIENCES LTD (IN) 2013-05-22 EP disclosed
US-7718690-B2 N-arylsulfonyl-3-aminoalkoxyindoles RAMAKRISHNA VENKATA SATYA NIROGI 2010-05-18 US disclosed
US-20090131507-A1 N-arylsulfonyl-3-aminoalkoxyindoles SUVEN LIFE SCIENCES LIMITED (IN) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131507-A1 N-arylsulfonyl-3-aminoalkoxyindoles HTR3C, HTR3A, AANAT ALDH1A1 1943/4885KDM4E 3751/4885LMNA 2672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.