Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 17/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 16/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512233 | 0.91 | NR1H3 (0.52) | MLYCDNR1H3NR1H2 | |
| SCHEMBL428959 | 0.84 | MLYCD (0.77) | MLYCDNR1H3NR1H2RORC | |
| SCHEMBL28135588 | 0.76 | MEN1 (0.50) | MLYCDNR1H3NR1H2 | |
| SCHEMBL5734655 | 0.76 | IDO1 (0.52) | — | |
| SCHEMBL121442 | 0.76 | — | — | |
| SCHEMBL9694180 | 0.75 | TSHR (0.46) | — | |
| SCHEMBL130133 | 0.75 | NR1H2 (0.62) | MLYCDNR1H3NR1H2 | |
| SCHEMBL6725714 | 0.74 | RORC (0.55) | MLYCDNR1H3RORC | |
| SCHEMBL18588555 | 0.73 | RORC (0.72) | MLYCDRORC | |
| SCHEMBL20302436 | 0.73 | IDO1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048920-A1 | Sulfone liver X-receptor modulators | PHARMACIA CORPORATION | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048920-A1 | Sulfone liver X-receptor modulators | NR1H2, NR1H3, NR1H4 | MLYCD 3570/4885NR1H3 2/4885NR1H2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.