Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820282 | 0.86 | TDP1 (0.42) | KDM4ETDP1MAPTALDH1A1PTGDR2 | |
| SCHEMBL6821088 | 0.85 | NPSR1 (0.35) | UTS2RMAPTALDH1A1NPSR1PTGDR2 | |
| SCHEMBL6820218 | 0.84 | UTS2R (0.44) | UTS2RHTR7TAAR1KDM4ETDP1 | |
| SCHEMBL6823545 | 0.84 | UTS2R (0.41) | UTS2RHTR7TAAR1KDM4EMAPT | |
| SCHEMBL6820713 | 0.82 | TDP1 (0.41) | HTR7KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL6820268 | 0.80 | UTS2R (0.42) | UTS2RHTR7TAAR1KDM4EMAPT | |
| SCHEMBL6820722 | 0.78 | UTS2R (0.52) | UTS2RHTR7TAAR1KDM4EMAPT | |
| SCHEMBL6821026 | 0.78 | KDM4E (0.41) | UTS2RHTR7KDM4ETDP1MAPT | |
| SCHEMBL6821067 | 0.78 | NPSR1 (0.33) | MAPTALDH1A1NPSR1 | |
| SCHEMBL3562582 | 0.77 | HTR6 (0.39) | UTS2RHTR7KDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |