Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821088 | 0.92 | NPSR1 (0.35) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6821158 | 0.88 | NPSR1 (0.34) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6820693 | 0.78 | UTS2R (0.46) | NPSR1MAPTALDH1A1 | |
| SCHEMBL6823545 | 0.73 | UTS2R (0.41) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6820268 | 0.72 | UTS2R (0.42) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6820218 | 0.70 | UTS2R (0.44) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6821018 | 0.64 | UTS2R (0.50) | MAPTALDH1A1 | |
| SCHEMBL6439888 | 0.64 | HTR6 (0.48) | ALDH1A1 | |
| SCHEMBL6821022 | 0.63 | TDP1 (0.41) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6439333 | 0.62 | HTR6 (0.45) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |