Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821018 | 0.93 | UTS2R (0.50) | UTS2RHTR7DRD2DRD1DRD4 | |
| SCHEMBL6820760 | 0.86 | DRD2 (0.43) | HTR7DRD2DRD1DRD4DRD5 | |
| SCHEMBL6817351 | 0.84 | UTS2R (0.50) | UTS2RHTR7DRD2DRD1DRD4 | |
| SCHEMBL6817341 | 0.84 | HTR7 (0.48) | UTS2RHTR7DRD2DRD1DRD4 | |
| SCHEMBL6817280 | 0.82 | HTR7 (0.45) | UTS2RHTR7DRD2DRD1DRD4 | |
| SCHEMBL6820726 | 0.79 | HTR7 (0.52) | UTS2RHTR7DRD2DRD1DRD4 | |
| SCHEMBL6820693 | 0.78 | UTS2R (0.46) | UTS2RHTR7TAAR1CSF1RMAPT | |
| SCHEMBL6817354 | 0.78 | HTR7 (0.48) | UTS2RHTR7DRD2DRD1DRD4 | |
| SCHEMBL6823917 | 0.77 | HTR7 (0.43) | UTS2RHTR7CSF1RKDM4EALDH1A1 | |
| SCHEMBL3557838 | 0.77 | HTR7 (0.43) | UTS2RHTR7CSF1RKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |