Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817250 | 0.90 | SMN1; SMN2 (0.38) | MAPTTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6821070 | 0.89 | APOL1 (0.36) | OPRM1RAB9ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6817272 | 0.84 | OPRM1 (0.34) | RXFP1OPRM1OPRL1MAPTCTSL | |
| SCHEMBL6820669 | 0.84 | OPRM1 (0.34) | RXFP1OPRM1OPRL1MAPTCTSL | |
| SCHEMBL5963561 | 0.68 | SLC6A2 (0.33) | RXFP1OPRM1CTSLCTSBCTSS | |
| SCHEMBL5963859 | 0.66 | SLC6A2 (0.33) | RXFP1OPRM1GAASIGMAR1SMN1; SMN2 | |
| SCHEMBL5963964 | 0.66 | LMNA (0.31) | RXFP1OPRM1OPRL1CTSLCTSB | |
| SCHEMBL5964017 | 0.64 | GRIN1 (0.36) | OPRM1MAPTSIGMAR1RAB9ANPC1 | |
| SCHEMBL14067363 | 0.60 | SMN1; SMN2 (0.68) | GAASMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL5963885 | 0.58 | MTNR1A (0.38) | RXFP1OPRM1OPRL1MAPTCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326851-B1 | SUBSTITUTED DIPEPTIDES AS GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2004-06-30 | — | — | EP | claimed |