Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817307 | 0.91 | HTR6 (0.47) | HTR6ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL6820226 | 0.87 | HTR6 (0.49) | HTR6ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL6820454 | 0.86 | HTR6 (0.61) | HTR6ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL6821057 | 0.86 | HTR6 (0.69) | HTR6ALDH1A1 | |
| SCHEMBL6817351 | 0.85 | UTS2R (0.50) | HTR6ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL6820760 | 0.82 | DRD2 (0.43) | HTR6ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL6919395 | 0.82 | HTR6 (0.42) | HTR6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6817280 | 0.81 | HTR7 (0.45) | HTR6ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL3556008 | 0.77 | HTR6 (0.53) | HTR6DRD2HTR1B | |
| SCHEMBL6820991 | 0.77 | HTR6 (0.52) | HTR6ALDH1A1KDM4EGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |