Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817310 | 0.90 | HTR7 (0.46) | HTR7SMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL6821018 | 0.89 | UTS2R (0.50) | HTR7SMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL6820760 | 0.89 | DRD2 (0.43) | HTR7SMN1; SMN2ALDH1A1KDM4EDRD2 | |
| SCHEMBL6820722 | 0.82 | UTS2R (0.52) | HTR7SMN1; SMN2ALDH1A1KDM4EDRD2 | |
| SCHEMBL6821065 | 0.81 | HTR6 (0.50) | SMN1; SMN2GAAALDH1A1KDM4EDRD2 | |
| SCHEMBL3936199 | 0.79 | HTR6 (0.43) | HTR7SMN1; SMN2ALDH1A1KDM4EDRD2 | |
| SCHEMBL6820963 | 0.79 | KDM4E (0.46) | HTR7SMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL6817307 | 0.78 | HTR6 (0.47) | GAAALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL6817341 | 0.78 | HTR7 (0.48) | HTR7ALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL6820226 | 0.77 | HTR6 (0.49) | HTR7ALDH1A1KDM4EDRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |