Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821067 | 0.88 | NPSR1 (0.33) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6823545 | 0.84 | UTS2R (0.41) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6821088 | 0.83 | NPSR1 (0.35) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6821022 | 0.71 | TDP1 (0.41) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6820693 | 0.68 | UTS2R (0.46) | NPSR1MAPTALDH1A1 | |
| SCHEMBL6821161 | 0.64 | ALDH1A1 (0.35) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6817341 | 0.62 | HTR7 (0.48) | ALDH1A1 | |
| SCHEMBL1045003 | 0.62 | TSHR (0.36) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6820735 | 0.62 | PLA2G2A (0.46) | KMT2ATSHRPLA2G1B | |
| SCHEMBL6821068 | 0.61 | HDAC1 (0.50) | NPSR1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |