Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820713 | 0.90 | TDP1 (0.41) | TDP1HTR7KMT2AMAPTMEN1 | |
| SCHEMBL6823545 | 0.88 | UTS2R (0.41) | HTR7KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6821006 | 0.83 | TDP1 (0.52) | TDP1KMT2AMAPTMEN1GAA | |
| SCHEMBL6820282 | 0.81 | TDP1 (0.42) | TDP1KMT2AMAPTMEN1GAA | |
| SCHEMBL7154224 | 0.78 | ESR1 (0.37) | TDP1HTR7MAPTGAAALDH1A1 | |
| SCHEMBL3556559 | 0.78 | HTR6 (0.45) | HTR7KMT2AMEN1ALDH1A1HTR6 | |
| SCHEMBL6817336 | 0.78 | ALDH1A1 (0.41) | TDP1HTR7KMT2AMAPTMEN1 | |
| SCHEMBL6817497 | 0.77 | TDP1 (0.52) | TDP1KMT2AMAPTMEN1GAA | |
| SCHEMBL6817310 | 0.76 | HTR7 (0.46) | HTR7GAAALDH1A1LTA4HHTR6 | |
| SCHEMBL6817320 | 0.75 | TDP1 (0.47) | TDP1KMT2AMAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |