Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 18/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA5A | P35218 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18228 | 0.81 | ALDH1A1 (0.36) | CCNE1CDK2CDK5CDK5R1CA2 | |
| SCHEMBL5152395 | 0.81 | CCNE1 (0.38) | CCNE1CDK2CDK5CDK5R1CA2 | |
| SCHEMBL5151946 | 0.81 | KMT2A (0.36) | CCNE1CDK2CDK5CDK5R1CA2 | |
| Hydrochloric Acid SCHEMBL28224660 | 0.79 | KMT2A (0.35) | CCNE1CDK2CDK5CDK5R1CA2 | |
| SCHEMBL10753718 | 0.74 | CCNE1 (0.32) | CCNE1CDK2CDK5CDK5R1CA2 | |
| SCHEMBL5230316 | 0.69 | CES1 (0.49) | CA2CA1CA9CA12 | |
| SCHEMBL9005006 | 0.69 | PTPRC (0.46) | — | |
| SCHEMBL2008068 | 0.69 | CA2 (0.52) | CA2CA1CA9CA12CA4 | |
| SCHEMBL2016370 | 0.69 | PTPRC (0.46) | — | |
| SCHEMBL5149907 | 0.69 | CA2 (0.52) | CCNE1CDK2CDK5CDK5R1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237523-B | Pyrimidine derivatives and preparation method thereof, purposes | 深圳市博圣康生物科技有限公司 | 2018-06-01 | — | — | CN | claimed |
| CN-105237523-A | Pyrimidine derivatives, and preparation method and use thereof | SHENZHEN BIOSCIEN PHARMACEUTICALS CO LTD | 2016-01-13 | — | — | CN | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| CN-105237523-B | Pyrimidine derivatives and preparation method thereof, purposes | 深圳市博圣康生物科技有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-105237523-A | Pyrimidine derivatives, and preparation method and use thereof | SHENZHEN BIOSCIEN PHARMACEUTICALS CO LTD | 2016-01-13 | — | — | CN | disclosed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| US-4645529-A | POSTEMERGENCE AND PREEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-02-24 | — | — | US | disclosed |
| US-4523943-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| US-4398939-A | Herbicidal thiophenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0017473-A1 | Herbicidal thiophenesulfonamides, and preparation, compositions and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-15 | — | — | EP | disclosed |