Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822164 | 0.90 | UTS2R (0.38) | UTS2RBRAFEGFRKDR | |
| SCHEMBL6674024 | 0.90 | LMNA (0.39) | UTS2RMEN1KMT2AALOX15MAPK1 | |
| SCHEMBL6818539 | 0.89 | UTS2R (0.36) | UTS2RKMT2ABRAFPSEN1PSEN2 | |
| SCHEMBL6824709 | 0.89 | UTS2R (0.36) | UTS2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6823783 | 0.87 | LMNA (0.43) | UTS2RMEN1KMT2AALOX15MAPK1 | |
| SCHEMBL6822523 | 0.85 | UTS2R (0.41) | UTS2RMEN1KMT2AALOX15MAPK1 | |
| SCHEMBL6824643 | 0.83 | UTS2R (0.35) | UTS2RMEN1KMT2ALMNA | |
| SCHEMBL6817378 | 0.83 | UTS2R (0.41) | UTS2RMEN1KMT2AALOX15MAPK1 | |
| SCHEMBL6821207 | 0.83 | ALDH1A1 (0.39) | UTS2RKMT2ALMNAHTT | |
| SCHEMBL6825132 | 0.81 | FFAR4 (0.41) | UTS2RMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043948-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043948-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |