Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.38 |
| ▸ | BRAF | P15056 | 4/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818539 | 0.92 | UTS2R (0.36) | UTS2RBRAFFFAR4 | |
| SCHEMBL6821545 | 0.90 | UTS2R (0.42) | UTS2RBRAFEGFRKDR | |
| SCHEMBL6824709 | 0.87 | UTS2R (0.36) | UTS2RFFAR4 | |
| SCHEMBL6822074 | 0.87 | UTS2R (0.38) | UTS2RBRAFFFAR4SLC22A12NR3C1 | |
| SCHEMBL6820297 | 0.86 | FFAR4 (0.43) | UTS2RFFAR4RORARORCNR1H2 | |
| SCHEMBL6824643 | 0.85 | UTS2R (0.35) | UTS2R | |
| SCHEMBL6820770 | 0.83 | UTS2R (0.37) | UTS2RBRAFFFAR4SLC22A12RORA | |
| SCHEMBL6825132 | 0.83 | FFAR4 (0.41) | UTS2RFFAR4SLC22A12 | |
| SCHEMBL6821207 | 0.82 | ALDH1A1 (0.39) | UTS2RFFAR4 | |
| SCHEMBL6824462 | 0.81 | PKM (0.37) | UTS2RFFAR4SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043948-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |