Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680164 | 0.92 | PTPN11 (0.34) | UTS2RPTPN11KCNH2MEN1KMT2A | |
| SCHEMBL6824709 | 0.87 | UTS2R (0.36) | UTS2RPPARGALDH1A1 | |
| SCHEMBL6818539 | 0.87 | UTS2R (0.36) | UTS2RKMT2A | |
| SCHEMBL6823530 | 0.86 | BRAF (0.38) | MEN1ALPLKMT2AALDH1A1LMNA | |
| SCHEMBL6820791 | 0.86 | FFAR4 (0.36) | — | |
| SCHEMBL6822164 | 0.85 | UTS2R (0.38) | UTS2R | |
| SCHEMBL6821207 | 0.85 | ALDH1A1 (0.39) | UTS2RKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL6821545 | 0.83 | UTS2R (0.42) | UTS2RMEN1KMT2ALMNA | |
| SCHEMBL6823531 | 0.83 | UTS2R (0.34) | UTS2R | |
| SCHEMBL6821099 | 0.82 | UTS2R (0.33) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043948-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043948-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |