Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27855068 | 0.81 | CYP2C19 (0.50) | LTA4HFBP1NPC1RAB9AADRB2 | |
| SCHEMBL27468396 | 0.81 | NR1H3 (0.51) | LTA4HFBP1MEN1NPC1KMT2A | |
| SCHEMBL2973461 | 0.81 | LTA4H (0.49) | LTA4HFBP1MEN1NPC1RAB9A | |
| SCHEMBL378027 | 0.80 | PDPK1 (0.50) | LTA4HNR1H3 | |
| SCHEMBL6163997 | 0.80 | CYP17A1 (0.50) | LTA4HADRB2LOXL2HRH3CYP17A1 | |
| SCHEMBL5533749 | 0.79 | LOXL2 (0.62) | LTA4HADRB2LOXL2ABL1BCR | |
| SCHEMBL7617248 | 0.78 | PDPK1 (0.48) | LTA4HNR1H3 | |
| Hydrochloric Acid SCHEMBL3930720 | 0.78 | PDPK1 (0.48) | LTA4HNR1H3 | |
| SCHEMBL12419334 | 0.77 | LTA4H (0.46) | LTA4HADRB2GAALOXL2CYP17A1 | |
| SCHEMBL558329 | 0.77 | LTA4H (0.56) | LTA4HFBP1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046141-A1 | NEW TRICYCLIC ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2004-06-03 | — | — | WO | disclosed |