Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247587 | 0.83 | NR1H3 (0.50) | NR1H3SLC6A3FFAR2POLBKDM4E | |
| SCHEMBL2973461 | 0.81 | LTA4H (0.49) | LTA4HALDH1A1POLBFBP1HPGD | |
| SCHEMBL27855068 | 0.81 | CYP2C19 (0.50) | LTA4HALDH1A1KDM4EFBP1CYP2C9 | |
| SCHEMBL6821892 | 0.81 | LTA4H (0.49) | NR1H3LTA4HFBP1NPC1ADRB2 | |
| SCHEMBL6163997 | 0.80 | CYP17A1 (0.50) | NR1H3SLC6A3LTA4HALDH1A1HPGD | |
| SCHEMBL378027 | 0.80 | PDPK1 (0.50) | NR1H3SLC6A3LTA4HALDH1A1KDM4E | |
| SCHEMBL5533749 | 0.79 | LOXL2 (0.62) | SLC6A3LTA4HADRB2LOXL2 | |
| SCHEMBL2269823 | 0.79 | FBP1 (0.45) | NR1H3ALDH1A1KDM4EFBP1HPGD | |
| SCHEMBL7617248 | 0.78 | PDPK1 (0.48) | NR1H3SLC6A3LTA4HALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3930720 | 0.78 | PDPK1 (0.48) | NR1H3SLC6A3LTA4HALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149191-C | Azetidine derivatives, Preparation and medicines containing them | ���ĵ�˹ҩ��ɷ�����˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1316991-A | Azetidine derivatives, preparation and medicines containing them | AVENTIS PHARMA SA (FR) | 2001-10-10 | — | — | CN | disclosed |