Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.49 |
| ▸ | CTSK | P43235 | 8/20 | 0.49 |
| ▸ | CTSL | P07711 | 11/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445473 | 0.90 | CTSS (0.49) | CTSSCTSKCTSLCTSBESR1 | |
| SCHEMBL6443700 | 0.90 | CTSS (0.54) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6442192 | 0.89 | ESR1 (0.40) | CTSSCTSKCTSLCTSBESR1 | |
| SCHEMBL6447927 | 0.88 | CTSK (0.52) | CTSSCTSKCTSLCTSBESR1 | |
| SCHEMBL6442258 | 0.88 | SMN1; SMN2 (0.48) | CTSSCTSKCTSLCTSBESR1 | |
| SCHEMBL6446709 | 0.88 | CTSS (0.53) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6442459 | 0.86 | SMN1; SMN2 (0.54) | CTSSCTSKCTSLCTSBESR1 | |
| SCHEMBL6446246 | 0.84 | CTSS (0.60) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6443482 | 0.84 | CTSS (0.44) | CTSSCTSKCTSLCTSBESR1 | |
| SCHEMBL6818834 | 0.82 | CTSS (0.48) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |