Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944875 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL15825692 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL7943009 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL14249242 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL15824542 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL8908184 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL716506 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL7942967 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL117939 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 | |
| SCHEMBL6822085 | 1.00 | BLM (0.57) | BLMLMNAPTPN1KDM1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137756-A1 | COMPOUNDS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | HONGENE BIOTECH CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |
| CN-116462578-B | Method for synthesizing delta-methyl ketone by one-pot method | 万华化学集团股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-116462578-A | Method for synthesizing delta-methyl ketone by one-pot method | 万华化学集团股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-9561989-B2 | Process of asymmetric hydrogenation of ketals and acetals | DSM IP ASSETS B.V. (NL) | 2017-02-07 | — | — | US | disclosed |
| US-20160185683-A1 | PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS | DSM IP ASSETS B.V. (NL) | 2016-06-30 | — | — | US | disclosed |
| US-20150321971-A1 | EFFICIENT PROCESS OF ASYMMETRIC HYDROGENATION OF UNSATURATED KETONES USING ADDITIVES | DSM IP ASSETS B.V. (NL) | 2015-11-12 | — | — | US | disclosed |
| EP-1122236-B1 | Process for producing 6-methyl-3-hepten-2-one, and process for producing phyton or isophytol | KURARAY CO (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-0816321-B1 | Process for producing 6-methyl-2-heptanone analogues, and process for producing phyton and isophytol | KURARAY CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-6288128-B1 | β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound | EISAI CO., LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-1122236-A2 | Process for producing 6-methyl-3-hepten-2-one, and process for producing phyton or isophytol | Kuraray Co., Ltd., Kurashiki Plant (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-6232506-B1 | SUBJECTING ISOVALERALDEHYDE AND ACETONE TO CROSS ALDOL CONDENSATION CARRIED OUT WHILE CONTINUOUSLY ADDING TO ACETONE BOTH ISOVALERALDEHYDE AND AQUEOUS ALKALI CONTAINING ALKALINE SUBSTANCE TO GIVE 6-METHYL-3-HEPTEN-2-ONE | KURARAY CO., LYD. (JP) | 2001-05-15 | — | — | US | disclosed |
| US-6111131-A | SUCH AS 3,7,11,15,19,23,27,31-OCTAMETHYL-2,6,10,14,18,22,26,30-DOTRIACONTAOCTAEN-1 -OL; USEFUL AS PROPHYLACTIC DRUG FOR IMMUNODEFICIENCY DISEASES AND INFECTIOUS DISEASES | EISAI CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| US-5955636-A | CROSS ALDOL CONDENSATION OF BRANCHED ALDEHYDE AND ACETONE; AQUEOUS ALKALI; HYDROGENATION CATALYST | KURARAY CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0816321-A1 | Process for producing 6-methyl-3-hepten-2-one and 6-methyl-2-heptanone analogues, and process for producing phyton or isophytol | KURARAY CO., LTD. (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5658958-A | β, γ-dihydropolyprenyl alcohol derivatives effective at mitigating stress in animals | EISAI CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5280048-A | Antiinfection agent | EISAI CO., LTD. (JP) | 1994-01-18 | — | — | US | disclosed |
| US-4624966-A | β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound | EISAI CO., LTD. (JP) | 1986-11-25 | — | — | US | disclosed |
| US-4169157-A | Therapeutic preparations for peptic ulcers comprising aliphatic ketone derivative | EISAI CO., LTD. (JP) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150321971-A1 | EFFICIENT PROCESS OF ASYMMETRIC HYDROGENATION OF UNSATURATED KETONES USING ADDITIVES | ADH5, ADH1A, ADH1C | BLM 4162/4885LMNA 3902/4885PTPN1 4844/4885 |
| US-20160185683-A1 | PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS | KAT5, AKR1D1, AKR1C2 | BLM 4344/4885LMNA 4292/4885PTPN1 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.