SCHEMBL6825485

SCHEMBL6825485

CC(C)(CNC(=O)Nc1ccc(Cl)cc1Cl)CC(=O)N(CC(=O)NO)CC1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.41
USP30 Q70CQ3 1/20 0.39
KMT2A Q03164 4/20 0.38
MAPK1 P28482 1/20 0.37
UBE2M P61081 1/20 0.37
DCUN1D1 Q96GG9 1/20 0.37
HTT P42858 1/20 0.37
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6824982 0.98 RAB9A (0.41) RAB9ANPC1USP30KMT2AMAPK1
SCHEMBL6825386 0.93 TP53 (0.38) RAB9AKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL6825899 0.92 RAB9A (0.42) RAB9ANPC1USP30KMT2AMAPK1
SCHEMBL6825911 0.91 TP53 (0.38) RAB9AKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL6822311 0.89 NPC1 (0.40) RAB9ANPC1
SCHEMBL6825073 0.89 MEN1 (0.39) KMT2AMEN1MAPTALDH1A1
SCHEMBL6825402 0.88 ALDH1A1 (0.49) KMT2AHTTLMNAMEN1SMN1; SMN2
SCHEMBL6827642 0.88 NPC1 (0.38) RAB9ANPC1
SCHEMBL6822142 0.86 KMT2A (0.49) KMT2AHTTLMNAMEN1SMN1; SMN2
SCHEMBL6827780 0.85 EPHX2 (0.53) RAB9ANPC1USP30KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO claimed