Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129112 | 0.82 | L3MBTL1 (0.59) | L3MBTL1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6060600 | 0.78 | PDE4B (0.60) | KMT2AALDH1A1MEN1MAPK1TUBB1 | |
| SCHEMBL7046987 | 0.78 | ALDH1A1 (0.72) | L3MBTL1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL9828028 | 0.78 | MEN1 (0.62) | L3MBTL1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6129091 | 0.78 | ALDH1A1 (0.62) | L3MBTL1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL25238149 | 0.77 | ALDH1A1 (0.60) | L3MBTL1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10483795 | 0.77 | ALDH1A1 (0.60) | L3MBTL1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL3407396 | 0.77 | MEN1 (0.65) | L3MBTL1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6129106 | 0.75 | KMT2A (0.55) | L3MBTL1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6507928 | 0.75 | ALDH1A1 (0.58) | L3MBTL1KMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812825-B1 | PROPENONE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2004-02-11 | — | — | EP | disclosed |
| US-5952355-A | 1-ETHER-SUBSTITUTED PHENYL-3-INDOL-3-YL-2-PROPEN-1-ONE DERIVATIVES; ANTITUMOR AND -CARCINOGENIC AGENTS; IMMUNOSUPPRESSANTS; AUTOIMMUNE DISEASES; SIDE EFFECT REDUCTION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0812825-A1 | PROPENONE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |