Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12841456 | 1.00 | NOS2 (0.50) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL4623634 | 0.84 | SLC6A4 (0.71) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL30501482 | 0.84 | SLC6A4 (0.71) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL8082370 | 0.84 | SLC6A4 (0.71) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL24177878 | 0.83 | SLC6A4 (0.56) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| Hydrochloric Acid SCHEMBL4625001 | 0.83 | SLC6A2 (0.71) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL6823741 | 0.82 | SLC6A2 (0.41) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL4624371 | 0.82 | SLC6A2 (0.68) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL2212613 | 0.82 | SLC6A2 (0.68) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL2633864 | 0.82 | SLC6A2 (0.68) | NOS2SLC6A2SLC6A4CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076229-A1 | ATOMOXETINE FORMULATIONS AND ASSOCIATED METHODS | WATSON LABORATORIES, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080145318-A1 | ATOMOXETINE FORMULATIONS AND ASSOCIATED METHODS | WATSON LABORATORIES | 2008-06-19 | — | — | US | disclosed |
| US-20080145318-A1 | ATOMOXETINE FORMULATIONS AND ASSOCIATED METHODS | WATSON LABORATORIES | 2008-06-19 | — | — | US | disclosed |
| EP-1379492-A1 | INHIBITOR OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002070457-A1 | INHIBITOR OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080145318-A1 | ATOMOXETINE FORMULATIONS AND ASSOCIATED METHODS | SLC6A4, SLC6A2, SLC6A3 | NOS2 2480/4885SLC6A2 2/4885SLC6A4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.